The plant kingdom offers a wide range of natural antioxidant and medicinal values. The pro-fertility potential of the ethanolic leaves extract of Newbouldia laevis were studied to ascertain its effects on some biochemical indices. Micronor, a synthetic progestin and NAC were administered orally to the respective groups of animals with 120mg/kg body weight for five (5) days to induce infertility before daily administration of the plant extract for 14 days. The phytochemical screening of the extract revealed thepresence of Alkaloids Terpenoids, Saponins, Tannins, Flavonoids and phenols. The high concentration of prolactin compared with the low concentration of LH and Estradiol in the infertile rats group were significant at (P<0.05) compared with the low concentration in rats treated with the extracts only and after micronor treatment in a dose dependent manner. The low CD 4 and CD 8 counts in the ratsgroup treated with extract only were significant compared with the counts after administration of the extract and following micronor treatment. The multi-factorial etiology of female infertility could be traced to hormonal dysfunction initiated by cellular susceptibility to immunological repression, which was shown to have been influenced in this study by the hormonalregulation and immunological influence of Newbouldia laevis. The studies suggest that Newbouldia laevisleaf extract treatment can ameliorate the effect of hormone induced pathologies and can serve as a pro-fertility plant.
Drug information centres are the places where registered pharmacists provide any drug related information to healthcare professionals and to public for better patient care. WHO recognises independent drug information centres, as a core component of national programs to promote the rational use of medicines. The services should include collecting, reviewing, evaluating, indexing and distributing information on drugs to health workers. This allows access to clinical experiences, libraries, research facilities and educational activities. In India physicians received the maximum drug information from the pharmaceutical company representatives. Most of the developing countries suffer from lack of drug information due to limited availability of current literature, poor documentation and less dissemination of little information available. In a part of routine pharmacy practice effective drug information and evaluation skills plays a major role.
The aims of first aid are to preserve and protect life, prevent further injury or deterioration of illness and help to promote recovery. The objectives of the study: To assess the existing knowledge of Primary school teachers regarding selected first aid measures, to evaluate the effectiveness of self-Instructional Module regarding selected first aid measures, to associate the post-test knowledge scores with the selected demographic variables. Hypotheses of the study H1: There is a significant difference between pre-test and post-test knowledge score regarding selected First Aid Measures among primary school teachers. Methods: A Quasi experimental evaluative study was conducted, using one group pretest – post-test research design non-probability convenient sampling technique was used to select 60 Primary school teachers working at selected primary schools of Ernakulam district. Based on the objectives and the hypothesis the data were analyzed and by using various statistical tests. Results: The result reveals that the overall score was 19.00 in the pre-test and 26.03 in the post test, 100% of primary school teachers had inadequate knowledge in the pre-test, after distribution of Self-instructional module Primary school Teachers 13 (21.67%) had moderately good knowledge and 47 (78.33%) had excellent knowledge regarding selected conditions of first aid. Paired ‘t’ test showed that there was a significant improvement between pre-test and post test scores with ‘t’ value of 22.30, P < 0.05. Interpretation and conclusion: The study findings revealed that Self-Instructional Module on selected conditions of first aid was effective in improving knowledge of primary school teachers.